INT28412

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Context Info
Confidence 0.75
First Reported 1986
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 6
Total Number 6
Disease Relevance 0.79
Pain Relevance 2.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (SUPT7L)
Anatomy Link Frequency
somatic cell 1
oocytes 1
SUPT7L (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 3 99.64 Very High Very High Very High
opioid receptor 1 99.00 Very High Very High Very High
Opioid 6 98.56 Very High Very High Very High
antagonist 6 98.28 Very High Very High Very High
noradrenaline 8 97.64 Very High Very High Very High
Desipramine 7 97.16 Very High Very High Very High
ketamine 10 96.78 Very High Very High Very High
spastic colon 1 90.88 High High
Catecholamine 1 90.08 High High
Opioid receptor 1 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Body Weight 1 93.24 High High
Asthma 1 91.92 High High
Functional Bowel Disorder 1 90.88 High High
Staphylococcus Infection 2 88.80 High High
Congenital Anomalies 1 86.32 High High
Bovine Mastitis 1 75.00 Quite High
INFLAMMATION 3 68.24 Quite High
Depression 1 64.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
cDNA sequence and expression of bovine prodynorphin.
Gene_expression (expression) of bovine associated with enkephalin
1) Confidence 0.75 Published 1997 Journal Gene Section Title Doc Link 9074507 Disease Relevance 0 Pain Relevance 0.30
A synthetic peptide Tyr-Pro-Tyr-Tyr (casoxin B) which is found in bovine and human kappa-casein, also showed opioid antagonist activity at 100 microM.
Gene_expression (found) of bovine associated with antagonist and opioid
2) Confidence 0.65 Published 1989 Journal J. Dairy Res. Section Abstract Doc Link 2760302 Disease Relevance 0 Pain Relevance 0.77
In both these medical disorders, serum antibodies reactive with ovalbumin or gliadin were restricted predominantly to the IgG4 isotype; however, IgG antibodies reactive with bovine milk antigens, notably casein, were often restricted to both the IgG2 and IgG4 isotypes.
Gene_expression (reactive) of bovine
3) Confidence 0.65 Published 1988 Journal Int. Arch. Allergy Appl. Immunol. Section Abstract Doc Link 3192305 Disease Relevance 0.18 Pain Relevance 0.09
Two analogues of bovine beta-casomorphin-7 and beta-casomorphin-5 containing a beta-homo phenylalanine in substitution of the phenylalanine in position 3 were synthesised and tested for their mu-opioid receptor affinity.
Gene_expression (synthesised) of bovine associated with opioid receptor
4) Confidence 0.65 Published 2000 Journal Bioorg. Med. Chem. Lett. Section Abstract Doc Link 10866377 Disease Relevance 0 Pain Relevance 0.12
Cow and quarter clinical signs as well as milk somatic cell concentrations, bovine serum albumin, electrical conductivity, and milk production were determined before and for 14 days after endotoxin inoculation.
Gene_expression (production) of bovine in somatic cell
5) Confidence 0.58 Published 1986 Journal Am. J. Vet. Res. Section Abstract Doc Link 3524329 Disease Relevance 0.61 Pain Relevance 0.09
Effects of the intravenous anaesthetic ketamine on the desipramine-sensitive noradrenaline transporter (NAT) were examined in cultured bovine adrenal medullary cells and in transfected Xenopus laevis oocytes expressing the bovine NAT (bNAT).
Gene_expression (expressing) of bovine in oocytes associated with desipramine, ketamine and noradrenaline
6) Confidence 0.58 Published 1998 Journal Naunyn Schmiedebergs Arch. Pharmacol. Section Abstract Doc Link 9774220 Disease Relevance 0 Pain Relevance 0.74

General Comments

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