INT284139

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Context Info
Confidence 0.12
First Reported 2008
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.45
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (EDNRB, EDNRA) signal transducer activity (EDNRB, EDNRA) cell proliferation (EDNRA)
signal transduction (EDNRA) aging (EDNRA)
Anatomy Link Frequency
superior 2
EDNRB (Homo sapiens)
EDNRA (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 41 99.26 Very High Very High Very High
agonist 1 68.28 Quite High
cytokine 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Kinase C 2 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Bile 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Right Ventricular Hypertrophy 1 97.78 Very High Very High Very High
Coronary Heart Disease 1 83.04 Quite High
Disease 12 78.92 Quite High
Pulmonary Hypertension 65 68.32 Quite High
Increased Venous Pressure Under Development 10 63.76 Quite High
Congenital Anomalies 4 5.00 Very Low Very Low Very Low
Dyspnea 4 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 3 5.00 Very Low Very Low Very Low
Stress 3 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, decreased right ventricular hypertrophy and enhanced survival were seen only with the dual ETA and ETB antagonist, suggesting that non-selective (ETA/ETB) might be superior to selective ETA antagonism (Jasmin et al 2001).
ETB Spec (might) Positive_regulation (superior) of Gene_expression (antagonism) of ETA in superior associated with right ventricular hypertrophy and antagonist
1) Confidence 0.12 Published 2008 Journal Drug design, development and therapy Section Body Doc Link PMC2761178 Disease Relevance 0.45 Pain Relevance 0.22

General Comments

This test has worked.

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