INT284148

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Context Info
Confidence 0.29
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.54
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (EDNRB) signal transducer activity (EDNRB)
Anatomy Link Frequency
endothelial cells 2
EDNRB (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 2 16.68 Low Low
Catecholamine 1 14.52 Low Low
Kinase C 2 8.40 Low Low
antagonist 41 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Bile 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Increased Venous Pressure Under Development 10 99.80 Very High Very High Very High
Hyperplasia 1 90.24 High High
Disease 12 80.16 Quite High
Pulmonary Hypertension 65 54.48 Quite High
Natriuresis 2 26.44 Quite Low
Stress 3 25.36 Quite Low
Hypoxia 1 18.00 Low Low
Congenital Anomalies 4 5.00 Very Low Very Low Very Low
Dyspnea 4 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Activation of ETB receptors on vascular smooth muscle causes vasoconstriction, whereas activation of ETB on endothelial cells stimulates the release of NO and prostacyclin, thus producing vasodilatory effects (Feger et al 1997).
Positive_regulation (stimulates) of Positive_regulation (activation) of ETB in endothelial cells associated with increased venous pressure under development
1) Confidence 0.29 Published 2008 Journal Drug design, development and therapy Section Body Doc Link PMC2761178 Disease Relevance 0.54 Pain Relevance 0

General Comments

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