INT284184

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.14
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Akt1, Pdgfrb) signal transduction (Akt1, Pdgfrb) nucleus (Akt1, Pdgfrb)
plasma membrane (Akt1, Pdgfrb) kinase activity (Akt1, Pdgfrb) transport (Akt1)
Akt1 (Mus musculus)
Pdgfrb (Mus musculus)
Pain Link Frequency Relevance Heat
Potency 7 44.92 Quite Low
pruritus 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myeloid Leukemia 56 86.72 High High
Apoptosis 3 52.32 Quite High
Disease 13 5.00 Very Low Very Low Very Low
Leukemia 12 5.00 Very Low Very Low Very Low
Philadelphia Chromosome 10 5.00 Very Low Very Low Very Low
Toxicity 5 5.00 Very Low Very Low Very Low
Cancer 5 5.00 Very Low Very Low Very Low
Blast Crisis 4 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 4 5.00 Very Low Very Low Very Low
Disease Progression 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although nilotinib and imatinib exhibit great selectivity for Bcr-Abl, Kit and Pdgf-R, these agents bind these kinases with different affinities.
kinases Binding (bind) of Pdgf-R
1) Confidence 0.00 Published 2008 Journal Drug design, development and therapy Section Body Doc Link PMC2761189 Disease Relevance 0.14 Pain Relevance 0

General Comments

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