INT284224

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.60
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Cd4) plasma membrane (Cd4) enzyme binding (Cd4)
Cd4 (Mus musculus)
Hivan1 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 19 99.60 Very High Very High Very High
chemokine 9 5.00 Very Low Very Low Very Low
potassium channel 2 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acquired Immune Deficiency Syndrome Or Hiv Infection 57 100.00 Very High Very High Very High
Disease Progression 1 79.20 Quite High
Immunodeficiency 2 77.76 Quite High
Sprains And Strains 4 75.56 Quite High
Disease 4 70.92 Quite High
Viremia 1 51.80 Quite High
Infection 6 30.16 Quite Low
Congenital Anomalies 2 5.84 Low Low
Hepatotoxicity 1 5.00 Very Low Very Low Very Low
Vomiting 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interactions between the HIV Env protein and CD4 lead to the exposure of the coreceptor-binding site, which includes the third variable loop (V3) of gp120 as well as the bridging sheet, a discontinuous epitope that is formed only after CD4 engagement.
CD4 Binding (Interactions) of HIV associated with acquired immune deficiency syndrome or hiv infection
1) Confidence 0.01 Published 2008 Journal Drug design, development and therapy Section Body Doc Link PMC2761192 Disease Relevance 0.60 Pain Relevance 0.14

General Comments

This test has worked.

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