INT284225

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Context Info
Confidence 0.30
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.26
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Cd4, Ccr5) endosome (Ccr5) enzyme binding (Cd4)
cell-cell signaling (Ccr5) cytoplasm (Ccr5) signal transducer activity (Ccr5)
Cd4 (Mus musculus)
Ccr5 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 19 71.76 Quite High
chemokine 9 5.00 Very Low Very Low Very Low
potassium channel 2 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acquired Immune Deficiency Syndrome Or Hiv Infection 57 97.40 Very High Very High Very High
Opportunistic Infections 1 42.12 Quite Low
Hepatotoxicity 1 41.08 Quite Low
Infection 6 5.00 Very Low Very Low Very Low
Sprains And Strains 4 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Immunodeficiency 2 5.00 Very Low Very Low Very Low
Congenital Anomalies 2 5.00 Very Low Very Low Very Low
Vomiting 1 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, TNX-355 targets CD4, PRO 542 is aimed at gp120, and PRO 140 and HGS004 bind CCR5.
CD4 Binding (bind) of CCR5
1) Confidence 0.30 Published 2008 Journal Drug design, development and therapy Section Body Doc Link PMC2761192 Disease Relevance 0.26 Pain Relevance 0.04

General Comments

This test has worked.

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