INT284299

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.51
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Adrb3) plasma membrane (Adrb3) nucleus (Adrb3)
signal transducer activity (Adrb3)
Anatomy Link Frequency
macrophages 2
Adrb3 (Mus musculus)
Mir155 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 5 95.92 Very High Very High Very High
Inflammatory mediators 1 81.16 Quite High
chemokine 3 79.96 Quite High
Inflammatory response 12 73.64 Quite High
Inflammation 13 21.20 Low Low
Arthritis 5 12.88 Low Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 10 98.92 Very High Very High Very High
Acute-phase Reaction 2 98.24 Very High Very High Very High
Infection 1 83.28 Quite High
INFLAMMATION 27 80.76 Quite High
Disease 7 17.28 Low Low
Arthritis 5 12.88 Low Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 2 5.00 Very Low Very Low Very Low
Neutropenia 2 5.00 Very Low Very Low Very Low
Body Weight 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In this study, we show that c/ebp Beta is a bona fide target of miR-155 and that LPS treatment of murine macrophages strongly induces miR-155 expression, leading to translational repression of c/ebp Beta.
Beta Positive_regulation (induces) of Gene_expression (expression) of miR-155 in macrophages associated with repression
1) Confidence 0.01 Published 2009 Journal Nucleic Acids Research Section Body Doc Link PMC2761263 Disease Relevance 0.51 Pain Relevance 0.24

General Comments

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