INT284329

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Context Info
Confidence 0.20
First Reported 2009
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.63
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (MTOR) Golgi apparatus (MTOR) endoplasmic reticulum (MTOR)
cytoplasm (MTOR) cytosol (MTOR) signal transduction (MTOR)
MTOR (Homo sapiens)
Pain Link Frequency Relevance Heat
positron emission tomography 4 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
local anesthetic 2 5.00 Very Low Very Low Very Low
lidocaine 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperplasia 2 97.56 Very High Very High Very High
Apoptosis 4 95.32 Very High Very High Very High
Cancer 210 84.12 Quite High
Adenocarcinoma 16 50.00 Quite Low
Lung Cancer 16 44.00 Quite Low
Thyroid Neoplasm 2 43.04 Quite Low
Hyperinsulinism 4 23.28 Low Low
Congenital Anomalies 2 15.68 Low Low
Metastasis 30 5.00 Very Low Very Low Very Low
Recurrence 22 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, in the patient, we observed LOH deletion in AKT1, under-expression of AKT2, mTOR, elF4E, and over-expression of the negative regulators eIF4EBP1 and NKX3-1.
Regulation (under) of Gene_expression (expression) of mTOR
1) Confidence 0.20 Published 2010 Journal Genome Biol Section Body Doc Link PMC2945784 Disease Relevance 0.82 Pain Relevance 0
However, in the patient, we observed LOH deletion in AKT1, under-expression of AKT2, mTOR, elF4E, and over-expression of the negative regulators eIF4EBP1 and NKX3-1.
Regulation (under) of Gene_expression (expression) of mTOR
2) Confidence 0.20 Published 2010 Journal Genome Biol Section Body Doc Link PMC2945784 Disease Relevance 0.81 Pain Relevance 0
Total protein expression of mTOR and S6K1 kinase was unchanged following the study diets (Figure 2).
Neg (unchanged) Regulation (unchanged) of Gene_expression (expression) of mTOR
3) Confidence 0.16 Published 2009 Journal Nutr Metab (Lond) Section Body Doc Link PMC2761378 Disease Relevance 0 Pain Relevance 0

General Comments

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