INT284335

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Context Info
Confidence 0.18
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.06
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IRS1) signal transduction (IRS1) plasma membrane (IRS1)
nucleus (IRS1) cytoplasm (IRS1) signal transducer activity (IRS1)
IRS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 1 64.76 Quite High
tolerance 2 5.00 Very Low Very Low Very Low
lidocaine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 1 64.76 Quite High
Insulin Resistance 14 5.00 Very Low Very Low Very Low
Overnutrition 14 5.00 Very Low Very Low Very Low
Diabetes Mellitus 5 5.00 Very Low Very Low Very Low
Hyperinsulinism 4 5.00 Very Low Very Low Very Low
Weight Gain 3 5.00 Very Low Very Low Very Low
Impaired Glucose Tolerance 2 5.00 Very Low Very Low Very Low
Obesity 2 5.00 Very Low Very Low Very Low
Cardiovascular Disease 1 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Five days of HC overfeeding resulted in significant increases in tyrosine phosphorylation of IRS-1 (Figure 1A), with no change in total IRS-1 protein expression compared to EC feeding (Figure 2).
Neg (no) Regulation (change) of Gene_expression (expression) of IRS-1
1) Confidence 0.18 Published 2009 Journal Nutr Metab (Lond) Section Body Doc Link PMC2761378 Disease Relevance 0.06 Pain Relevance 0.03

General Comments

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