INT284385

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.22
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (ABCA1) small molecule metabolic process (ABCA1) Golgi apparatus (ABCA1)
ATPase activity (ABCA1) plasma membrane (ABCA1) intracellular (ABCA1)
ABCA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 46 92.64 High High
Inflammation 16 55.08 Quite High
rheumatoid arthritis 7 5.00 Very Low Very Low Very Low
Multiple sclerosis 4 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
Potency 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Neuropathic pain 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 12 55.44 Quite High
INFLAMMATION 16 55.08 Quite High
Cancer 41 54.40 Quite High
Solid Tumor 1 45.48 Quite Low
Skin Cancer 5 37.08 Quite Low
Breast Cancer 6 16.68 Low Low
Toxicity 11 5.00 Very Low Very Low Very Low
Metastasis 9 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 7 5.00 Very Low Very Low Very Low
Anaerobic Bacterial Infections 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
L(20)GAALSGLCLLSALALL(36) is required for this unique membrane localization as a signal anchor [2].
Positive_regulation (required) of Localization (localization) of membrane
1) Confidence 0.02 Published 2011 Journal Biochemistry Research International Section Body Doc Link PMC2989751 Disease Relevance 0.22 Pain Relevance 0.25
This controversy, however, may reflect the possibility that different peptides utilize different uptake mechanisms depending on their cargo and biophysical properties, or that CPP membrane translocation is mediated by several different pathways that may occur simultaneously (47).
Positive_regulation (mediated) of Localization (translocation) of membrane
2) Confidence 0.01 Published 2008 Journal AAPS J Section Body Doc Link PMC2761699 Disease Relevance 0 Pain Relevance 0

General Comments

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