INT2844

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Context Info
Confidence 0.70
First Reported 1979
Last Reported 2009
Negated 0
Speculated 1
Reported most in Abstract
Documents 6
Total Number 6
Disease Relevance 3.92
Pain Relevance 2.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (ID1) cytoplasm (ID1)
Anatomy Link Frequency
hepatocytes 1
kidney 1
ID1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Migraine 11 100.00 Very High Very High Very High
Analgesic 2 97.94 Very High Very High Very High
headache 10 97.52 Very High Very High Very High
cINOD 2 95.52 Very High Very High Very High
Paracetamol 2 82.56 Quite High
metalloproteinase 4 50.00 Quite Low
Snapping jaw 2 50.00 Quite Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Headache 21 100.00 Very High Very High Very High
Stomach Cancer 12 99.84 Very High Very High Very High
Cancer 10 99.68 Very High Very High Very High
Death 2 98.96 Very High Very High Very High
Renal Disease 2 95.16 Very High Very High Very High
Uremia 3 94.36 High High
Emergencies 3 92.24 High High
INFLAMMATION 1 64.48 Quite High
Temporomandibular Joint Syndrome 2 50.00 Quite Low
Anaemia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Id-1, one of the repressed genes, is upregulated in gastric cancers and has positive role in tumor progression and histogenesis of intestinal-type cancers.
Positive_regulation (upregulated) of Id-1 associated with cancer and stomach cancer
1) Confidence 0.70 Published 2006 Journal Int. J. Cancer Section Abstract Doc Link 16184548 Disease Relevance 1.03 Pain Relevance 0
The transcription factors, E2F1 and ID1 mRNA were increased three-fold and six-fold (P < 0.05, P < 0.01), respectively, in AFB(1) treated primary human hepatocytes but were not altered in HepG2.
Positive_regulation (increased) of ID1 in hepatocytes
2) Confidence 0.69 Published 2004 Journal Mutat. Res. Section Abstract Doc Link 15120964 Disease Relevance 0 Pain Relevance 0.15
Id-1 gene downregulation by sulindac sulfide and its upregulation during tumor development in gastric cancer.
Positive_regulation (upregulation) of Id-1 associated with cancer and stomach cancer
3) Confidence 0.47 Published 2006 Journal Int. J. Cancer Section Title Doc Link 16184548 Disease Relevance 0.52 Pain Relevance 0.10
We investigated the possibility of using ID-Migraine (ID-M) to improve migraine recognition in the ED setting.
Spec (investigated) Positive_regulation (using) of ID-M associated with migraine
4) Confidence 0.05 Published 2009 Journal Cephalalgia Section Abstract Doc Link 19438919 Disease Relevance 1.88 Pain Relevance 1.69
Determinations of immuno-detectable Erythropoietin (idEP), haematocrit (Hct), reticulocyte counts (RC) and serum iron (SI) in uraemic patients with different kidney diseases (KD) and various lengths of chronic haemodialysis treatment (HDT) revealed firstly that all patients had normal idEP, except for analgesic nephropathies who had significantly higher idEP levels; secondly that over six years of haemodialysis idEP increased by about 40% but without concomitant Hct improvement and thirdly that there were no clear interdependencies between Hct, SI, RC and idEP in uraemic patients.
Positive_regulation (increased) of idEP in kidney associated with analgesic, renal disease and uremia
5) Confidence 0.01 Published 1979 Journal Proc Eur Dial Transplant Assoc Section Abstract Doc Link 548991 Disease Relevance 0.43 Pain Relevance 0.10
Ninety-two-kilodalton proMMP-9 and its 121-kD complex form, as well as 72-kD proMMP-2 were significantly increased in the mild TMJ-ID group (P <.05 in all cases).
Positive_regulation (increased) of TMJ-ID
6) Confidence 0.00 Published 2001 Journal Oral Surg Oral Med Oral Pathol Oral Radiol Endod Section Body Doc Link 11346728 Disease Relevance 0.06 Pain Relevance 0

General Comments

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