INT284450

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.30
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Edn1, MMP9) extracellular region (Edn1, MMP9) peptidase activity (MMP9)
proteinaceous extracellular matrix (MMP9) extracellular matrix organization (MMP9) protein complex (MMP9)
Edn1 (Mus musculus)
MMP9 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 4 100.00 Very High Very High Very High
Inflammation 31 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Bioavailability 3 5.00 Very Low Very Low Very Low
Inflammatory mediators 3 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
qutenza 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Atherosclerosis 53 85.44 High High
Rupture 1 78.08 Quite High
Acute Coronary Syndrome 1 75.04 Quite High
Cardiovascular Disease 4 37.92 Quite Low
Asthma 4 12.44 Low Low
INFLAMMATION 29 5.00 Very Low Very Low Very Low
Stress 19 5.00 Very Low Very Low Very Low
Disorder Of Lipid Metabolism 9 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Toxicity 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Increased expression and activity of MMP-9 was shown to be ET-1 mediated and also present in a small cohort of humans exposed to diesel exhausts [118].
ET-1 Positive_regulation (mediated) of Gene_expression (expression) of MMP-9 associated with metalloproteinase
1) Confidence 0.01 Published 2009 Journal Part Fibre Toxicol Section Body Doc Link PMC2761850 Disease Relevance 0.30 Pain Relevance 0.18

General Comments

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