INT284481

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.39
Pain Relevance 0.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (ABCA1) small molecule metabolic process (ABCA1) Golgi apparatus (ABCA1)
intracellular (ABCA1) lipid metabolic process (ABCA1) extracellular space (Ighg1)
ABCA1 (Homo sapiens)
Ighg1 (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 33 98.64 Very High Very High Very High
Infliximab 31 97.86 Very High Very High Very High
cytokine 1 95.24 Very High Very High Very High
Adalimumab 1 93.92 High High
Etanercept 1 92.72 High High
Inflammation 3 69.96 Quite High
abatacept 1 64.40 Quite High
Arthritis 3 63.00 Quite High
cINOD 2 5.00 Very Low Very Low Very Low
Rheumatism 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 35 98.64 Very High Very High Very High
Necrosis 1 93.88 High High
Cancer 1 93.52 High High
Disease 12 89.08 High High
Genetic Predisposition To Disease 1 80.92 Quite High
INFLAMMATION 3 69.96 Quite High
Autoimmune Disease 3 65.16 Quite High
Rheumatic Diseases 2 5.00 Very Low Very Low Very Low
Hepatitis 1 5.00 Very Low Very Low Very Low
Myocardial Infarction 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Infliximab was the first TNF alpha blocker for RA treatment to be clinically tested and is a genetically constructed IgG1 murine-human chimeric monoclonal antibody that binds both to the soluble subunit as well as the membrane-bound precursor of TNF-alpha [4].
membrane-bound Binding (binds) of IgG1 associated with infliximab and rheumatoid arthritis
1) Confidence 0.00 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2762038 Disease Relevance 1.39 Pain Relevance 0.70

General Comments

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