INT284504

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Context Info
Confidence 0.03
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.20
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (ITGAL, ITGAM) plasma membrane (ITGAL, ITGAM) signal transduction (ITGAL)
Anatomy Link Frequency
cervix 3
myometrium 1
ITGAL (Homo sapiens)
ITGAM (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 10 63.92 Quite High
Inflammation 16 8.72 Low Low
chemokine 2 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 4 99.04 Very High Very High Very High
Eclampsia 2 44.68 Quite Low
INFLAMMATION 18 8.72 Low Low
Premature Birth 8 5.00 Very Low Very Low Very Low
Diabetes Mellitus 2 5.00 Very Low Very Low Very Low
Hypertension 2 5.00 Very Low Very Low Very Low
Pregnancy Complications 2 5.00 Very Low Very Low Very Low
Paresis 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Infection 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Neutrophil and monocyte adhesion to myometrial and cervical endothelium will be promoted during parturition by the increased CD11a and CD11b expression which we demonstrated: CD11a and b mediate binding to ICAM-1, which we previously showed was up-regulated in endothelium of human cervix and myometrium during labour (Ledingham et al., 2001).
CD11a Positive_regulation (promoted) of Gene_expression (expression) of CD11b in cervix associated with adhesions
1) Confidence 0.03 Published 2009 Journal Molecular Human Reproduction Section Body Doc Link PMC2762373 Disease Relevance 0.10 Pain Relevance 0.03
Neutrophil and monocyte adhesion to myometrial and cervical endothelium will be promoted during parturition by the increased CD11a and CD11b expression which we demonstrated: CD11a and b mediate binding to ICAM-1, which we previously showed was up-regulated in endothelium of human cervix and myometrium during labour (Ledingham et al., 2001).
CD11a Positive_regulation (promoted) of in myometrium Gene_expression (expression) of CD11b in cervix associated with adhesions
2) Confidence 0.01 Published 2009 Journal Molecular Human Reproduction Section Body Doc Link PMC2762373 Disease Relevance 0.10 Pain Relevance 0.03

General Comments

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