INT284552

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Context Info
Confidence 0.03
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.32
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Mthfd1) oxidoreductase activity (Mthfd1) ligase activity (Mthfd1)
cytoplasm (Mthfd1)
Anatomy Link Frequency
mast cells 1
T cells 1
Cd8a (Mus musculus)
Mthfd1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 45 82.68 Quite High
cytokine 13 54.56 Quite High
agonist 21 5.00 Very Low Very Low Very Low
complementary and alternative medicine 10 5.00 Very Low Very Low Very Low
corticosteroid 5 5.00 Very Low Very Low Very Low
Kinase C 4 5.00 Very Low Very Low Very Low
substance P 4 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
isoflurane 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 51 98.00 Very High Very High Very High
Severe Acute Respiratory Syndrome 38 85.12 High High
INFLAMMATION 47 82.68 Quite High
Coronavirus Infection 28 80.32 Quite High
Influenza Virus Infection 8 77.00 Quite High
Pulmonary Disease 2 76.48 Quite High
Disease 36 75.04 Quite High
Hypersensitivity 95 74.68 Quite High
Adult Respiratory Distress Syndrome 3 62.16 Quite High
General Immunology 14 60.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recently, a secondary peripheral interaction of CD8 T cells with antigen-bearing rDCs in the lung was found important for effective antiviral immunity [16].
CD8 Binding (interaction) of rDCs in T cells
1) Confidence 0.03 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2762542 Disease Relevance 0.99 Pain Relevance 0.07
By analyzing mast cell-deficient mice as well as those having local mast cell reconstitution, we observed that mast cells are required for the recruitment of CD8+ and pDCs but not CD11b+ DCs into the lymph node in response to intradermal administration of PGN.
CD8 Binding (recruitment) of DCs in mast cells
2) Confidence 0.00 Published 2007 Journal Allergy Asthma Clin Immunol Section Body Doc Link PMC2875553 Disease Relevance 0.32 Pain Relevance 0.03

General Comments

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