INT284558

Context Info Confidence 0.14 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0.24 Pain Relevance 0.17

signal transduction (Tlr4) plasma membrane (Tlr4) intracellular (Tlr4) cytoplasm (Tlr4)

Anatomy Link Frequency poly 2 Tlr4 (Mus musculus) Mat1a (Mus musculus)

Pain Link Frequency Relevance Heat agonist 22 98.04 Inflammatory response 2 21.92 Inflammation 32 5.00 cytokine 12 5.00 isoflurane 6 5.00 chemokine 2 5.00 anesthesia 2 5.00

Disease Link Frequency Relevance Heat Death 2 64.12 Infection 86 56.32 Severe Acute Respiratory Syndrome 76 50.00 Disease 48 50.00 INFLAMMATION 34 21.56 Coronavirus Infection 56 5.00 Influenza Virus Infection 16 5.00 Sprains And Strains 10 5.00 Respiratory Syncytial Virus 8 5.00 Lymphopenia 6 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

To determine whether poly I:C or LPS directly activated AMs, AMs were isolated and stimulated in vitro with both agonists.

LPS Positive_regulation (activated) of AMs in poly associated with agonist

1) Confidence 0.14 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2762542 Disease Relevance 0.12 Pain Relevance 0.09

To determine whether poly I:C or LPS directly activated AMs, AMs were isolated and stimulated in vitro with both agonists.

LPS Positive_regulation (activated) of AMs in poly associated with agonist

2) Confidence 0.06 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2762542 Disease Relevance 0.12 Pain Relevance 0.09

General Comments

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