INT284563

Context Info Confidence 0.22 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 2 Disease Relevance 2.43 Pain Relevance 0

endosome (Tlr3) signal transduction (Tlr3) endoplasmic reticulum (Tlr3) RNA binding (Tlr3) intracellular (Tlr3) cytoplasm (Tlr3)

Anatomy Link Frequency poly 2 Tlr3 (Mus musculus) Mat1a (Mus musculus)

Pain Link Frequency Relevance Heat Inflammation 32 5.00 agonist 22 5.00 cytokine 12 5.00 isoflurane 6 5.00 chemokine 2 5.00 anesthesia 2 5.00 Inflammatory response 2 5.00

Disease Link Frequency Relevance Heat Hypersensitivity 2 92.96 Infection 86 89.44 Severe Acute Respiratory Syndrome 76 85.84 Disease 48 75.00 Respiratory Disease 6 71.48 Coronavirus Infection 56 61.84 Lymphopenia 6 55.60 INFLAMMATION 34 5.00 Influenza Virus Infection 16 5.00 Sprains And Strains 10 5.00

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Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The inhibitory effects of AM can also be nullified if mice or AMs are pretreated with poly I:C, which directly activate AMs and rDCs through toll-like receptors 3 (TLR3).

toll-like receptors 3 Positive_regulation (activate) of AMs in poly

1) Confidence 0.22 Published 2009 Journal PLoS Pathogens Section Abstract Doc Link PMC2762542 Disease Relevance 1.21 Pain Relevance 0

The inhibitory effects of AM can also be nullified if mice or AMs are pretreated with poly I:C, which directly activate AMs and rDCs through toll-like receptors 3 (TLR3).

TLR3 Positive_regulation (activate) of AMs in poly

2) Confidence 0.22 Published 2009 Journal PLoS Pathogens Section Abstract Doc Link PMC2762542 Disease Relevance 1.22 Pain Relevance 0

General Comments

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