INT284683

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Context Info
Confidence 0.03
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.64
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Hsd17b6) endoplasmic reticulum (Hsd17b6)
Anatomy Link Frequency
plasma 1
Hsd17b6 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
positron emission tomography 156 95.92 Very High Very High Very High
medulla 90 95.44 Very High Very High Very High
Hippocampus 15 95.08 Very High Very High Very High
amygdala 9 92.36 High High
imagery 27 5.00 Very Low Very Low Very Low
agonist 18 5.00 Very Low Very Low Very Low
Central nervous system 9 5.00 Very Low Very Low Very Low
fifth nerve 6 5.00 Very Low Very Low Very Low
Multiple sclerosis 6 5.00 Very Low Very Low Very Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Herpes Simplex Encephalitis 123 100.00 Very High Very High Very High
Cold Sores 66 20.32 Low Low
Neurological Disease 33 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 18 5.00 Very Low Very Low Very Low
Disease 18 5.00 Very Low Very Low Very Low
INFLAMMATION 12 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 9 5.00 Very Low Very Low Very Low
Demyelinating Disease 6 5.00 Very Low Very Low Very Low
Death 6 5.00 Very Low Very Low Very Low
Injury 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The ex vivo biodistribution showed an increased binding in HSE rats as compared to controls and a decreased binding after pre-treatment with PK11195, for all three PET tracers.
HSE Binding (binding) of associated with positron emission tomography and herpes simplex encephalitis
1) Confidence 0.03 Published 2009 Journal Mol Imaging Biol Section Body Doc Link PMC2763079 Disease Relevance 0.17 Pain Relevance 0.12
After correction for plasma activity, the specific binding in both control and HSE rats was found to be significantly higher for [11C]-DPA-713 than for [11C]-(R)-PK11195.
HSE Binding (binding) of in plasma associated with herpes simplex encephalitis
2) Confidence 0.02 Published 2009 Journal Mol Imaging Biol Section Body Doc Link PMC2763079 Disease Relevance 0.17 Pain Relevance 0
No significant differences in specific binding in HSE rats were found between [11C]-(R)-PK11195 and [18F]-DPA-714.


HSE Binding (binding) of associated with herpes simplex encephalitis
3) Confidence 0.02 Published 2009 Journal Mol Imaging Biol Section Body Doc Link PMC2763079 Disease Relevance 0.30 Pain Relevance 0.26

General Comments

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