INT284684

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.36
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Map3k12) plasma membrane (Map3k12) cytoplasm (Map3k12)
Map3k12 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 12 88.12 High High
positron emission tomography 104 42.72 Quite Low
imagery 18 9.60 Low Low
medulla 60 5.00 Very Low Very Low Very Low
Hippocampus 10 5.00 Very Low Very Low Very Low
Central nervous system 6 5.00 Very Low Very Low Very Low
amygdala 6 5.00 Very Low Very Low Very Low
fifth nerve 4 5.00 Very Low Very Low Very Low
Multiple sclerosis 4 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Herpes Simplex Encephalitis 82 85.28 High High
Neurodegenerative Disease 6 78.04 Quite High
Cold Sores 44 64.28 Quite High
Neurological Disease 22 35.04 Quite Low
Urological Neuroanatomy 12 5.00 Very Low Very Low Very Low
Disease 12 5.00 Very Low Very Low Very Low
INFLAMMATION 8 5.00 Very Low Very Low Very Low
Demyelinating Disease 4 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Injury 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Another remarkable finding in this study was that the binding of [18F]-DPA-714 and [11C]-DPA-713 in the adrenals could not be blocked by pre-treatment with PK11195, whereas pre-treatment did block the binding of [11C]-(R)-PK11195.
Negative_regulation (block) of PK11195 Binding (binding) of
1) Confidence 0.01 Published 2009 Journal Mol Imaging Biol Section Body Doc Link PMC2763079 Disease Relevance 0.21 Pain Relevance 0.10
In addition, the non-specific binding of [18F]-DPA-714 was found to be lower than the non-specific [11C]-(R)-PK11195 binding.
Negative_regulation (lower) of PK11195 Binding (binding) of
2) Confidence 0.01 Published 2009 Journal Mol Imaging Biol Section Body Doc Link PMC2763079 Disease Relevance 0.15 Pain Relevance 0

General Comments

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