INT284689

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.59
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Map3k12) mitochondrion (Tspo) aging (Tspo)
plasma membrane (Map3k12) cytoplasm (Map3k12) response to stress (Tspo)
Anatomy Link Frequency
microglia 1
Tspo (Rattus norvegicus)
Map3k12 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
positron emission tomography 52 95.28 Very High Very High Very High
Multiple sclerosis 2 90.56 High High
imagery 9 85.44 High High
Central nervous system 3 68.32 Quite High
Inflammatory response 2 38.04 Quite Low
antagonist 1 20.48 Low Low
medulla 30 5.00 Very Low Very Low Very Low
agonist 6 5.00 Very Low Very Low Very Low
Hippocampus 5 5.00 Very Low Very Low Very Low
amygdala 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stroke 2 91.68 High High
Demyelinating Disease 2 90.56 High High
Neurological Disease 11 89.12 High High
Herpes Simplex Encephalitis 41 88.40 High High
Disease 6 85.36 High High
Injury 2 59.32 Quite High
Chronic Disease 1 45.92 Quite Low
Death 2 45.12 Quite Low
INFLAMMATION 4 37.68 Quite Low
Neurodegenerative Disease 3 30.92 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PET has already been used in numerous clinical studies to visualize activated microglia cells using the isoquinoline [11C]-(R)-PK11195 ((R)-N-methyl-N-(1-methylpropyl)-1-(2-chlorophenyl)isoquinoline-3-carboxamide) as the tracer. [11C]-(R)-PK11195 is a ligand for the TSPO.
TSPO Binding (ligand) of PK11195 in microglia associated with positron emission tomography
1) Confidence 0.00 Published 2009 Journal Mol Imaging Biol Section Body Doc Link PMC2763079 Disease Relevance 0.59 Pain Relevance 0.32

General Comments

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