INT284851

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Context Info
Confidence 0.25
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.73
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (S100a10)
Anatomy Link Frequency
A11 2
S100a10 (Mus musculus)
Pain Link Frequency Relevance Heat
tetrodotoxin 13 76.08 Quite High
Neuritis 1 73.84 Quite High
Analgesic 2 63.72 Quite High
sodium channel 11 50.00 Quite Low
Eae 1 48.72 Quite Low
Pain 5 41.64 Quite Low
IPN 1 33.00 Quite Low
withdrawal 2 12.60 Low Low
Acute pain 1 5.24 Low Low
amygdala 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Alzheimer's Dementia 89 99.42 Very High Very High Very High
Neuritis 1 73.84 Quite High
Cognitive Disorder 3 50.16 Quite High
Targeted Disruption 11 49.28 Quite Low
Pain 7 41.64 Quite Low
Inflammatory Pain 1 33.00 Quite Low
Dementia 6 5.00 Very Low Very Low Very Low
Motor Neuron Diseases 6 5.00 Very Low Very Low Very Low
Parkinson's Disease 5 5.00 Very Low Very Low Very Low
Frontotemporal Lobar Degeneration 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The calculated copy numbers of p11mRNA were 7329 ± 187 (wild type) and 23892 ± 89 (Pdzd2-deficient mice) respectively, thus the expression of p11 mRNA in DRG was significantly (3.3-fold) increased in Pdzd2-deficient mice as compared with wild type animals (Fig. 5D).


Positive_regulation (increased) of Gene_expression (expression) of p11 mRNA
1) Confidence 0.25 Published 2009 Journal Mol Cell Neurosci Section Body Doc Link PMC2764382 Disease Relevance 0 Pain Relevance 0.20
oligomer levels in the brains of the 3×Tg-AD mice, we performed dot blot experiments using A11, an oligomeric-specific antibody that recognizes high molecular weight A?
Positive_regulation (experiments) of Gene_expression (using) of A11 in A11 associated with alzheimer's dementia
2) Confidence 0.03 Published 2010 Journal Mol Neurodegener Section Body Doc Link PMC2989316 Disease Relevance 0.73 Pain Relevance 0.07

General Comments

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