INT284853

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Context Info
Confidence 0.21
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (S100a10, Pdzd2) extracellular region (Pdzd2) nucleus (Pdzd2)
cytoplasm (Pdzd2)
S100a10 (Mus musculus)
Pdzd2 (Mus musculus)
Pain Link Frequency Relevance Heat
sodium channel 11 100.00 Very High Very High Very High
Pain threshold 1 23.12 Low Low
tetrodotoxin 13 14.16 Low Low
Pain 5 5.00 Very Low Very Low Very Low
Analgesic 2 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Acute pain 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
nav1.8 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nociception 3 81.12 Quite High
Pain 7 23.12 Low Low
Targeted Disruption 7 11.12 Low Low
Inflammatory Pain 1 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Unlike p11 which binds exclusively to NaV1.8 among the voltage-gated sodium channels (Poon et al., 2004), Pdzd2 also binds to NaV1.7.
p11 Binding (binds) of Pdzd2 associated with sodium channel
1) Confidence 0.21 Published 2009 Journal Mol Cell Neurosci Section Body Doc Link PMC2764382 Disease Relevance 0.08 Pain Relevance 0.09

General Comments

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