INT284857

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Context Info
Confidence 0.16
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.30
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Nav1) endoplasmic reticulum (S100a10) cytoskeleton (Nav1)
cytoplasm (Nav1)
Anatomy Link Frequency
plasma 2
S100a10 (Mus musculus)
Nav1 (Mus musculus)
Pain Link Frequency Relevance Heat
withdrawal 2 80.76 Quite High
Pain threshold 1 71.08 Quite High
nociceptor 1 61.20 Quite High
sodium channel 11 50.00 Quite Low
tetrodotoxin 13 5.00 Very Low Very Low Very Low
Pain 5 5.00 Very Low Very Low Very Low
Analgesic 2 5.00 Very Low Very Low Very Low
Acute pain 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 7 93.84 High High
Pain 7 71.08 Quite High
Nociception 3 41.96 Quite Low
Inflammatory Pain 1 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These contradictions may be explained by the significant compensatory upregulation of p11mRNA in DRG of the Pdzd2-deficient mice, as the fact that p11 promotes the functional expression of NaV1.8 into the plasma membrane of sensory neurons.
p11 Positive_regulation (promotes) of Gene_expression (expression) of NaV1 in plasma
1) Confidence 0.16 Published 2009 Journal Mol Cell Neurosci Section Body Doc Link PMC2764382 Disease Relevance 0.30 Pain Relevance 0.17

General Comments

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