INT284868

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Context Info
Confidence 0.36
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.70
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Scn5a) plasma membrane (Scn5a) transmembrane transport (Scn5a)
Scn5a (Mus musculus)
Pain Link Frequency Relevance Heat
Action potential 32 92.48 High High
sodium channel 1 72.68 Quite High
Eae 3 49.52 Quite Low
fibrosis 22 5.00 Very Low Very Low Very Low
addiction 7 5.00 Very Low Very Low Very Low
action potential duration 5 5.00 Very Low Very Low Very Low
imagery 5 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Nav1.1 2 5.00 Very Low Very Low Very Low
nav1.3 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Heart Arrhythmia 25 96.36 Very High Very High Very High
Rheumatoid Arthritis 1 85.28 High High
Aging 10 79.92 Quite High
Cv General 2 Under Development 1 77.68 Quite High
Arrhythmias 2 Under Development 27 70.80 Quite High
Dislocations 2 67.68 Quite High
Heart Disease 1 61.04 Quite High
Targeted Disruption 10 50.00 Quite Low
Disease 4 50.00 Quite Low
Anxiety Disorder 2 43.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Loss-of-function mutations of SCN5A are associated to the inherited form of progressive cardiac conduction defect [1], [2] (PCCD) and to the Brugada syndrome (BrS) [3]–[5].
SCN5A Binding (associated) of associated with heart arrhythmia
1) Confidence 0.36 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824822 Disease Relevance 0.55 Pain Relevance 0.05
Oligos for Scn3b, Scn5a, and Scn1b were FAM/TAMRA labelled (Applied Biosystems).
Scn5a Binding (Oligos) of
2) Confidence 0.35 Published 2008 Journal Prog Biophys Mol Biol Section Body Doc Link PMC2764399 Disease Relevance 0.15 Pain Relevance 0.04

General Comments

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