INT284871

Context Info Confidence 0.44 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.27 Pain Relevance 0.04

transport (Scn1b)

Anatomy Link Frequency ventricles 1 Scn1b (Mus musculus)

Pain Link Frequency Relevance Heat Action potential 26 79.28 addiction 5 5.00 action potential duration 5 5.00 Eae 3 5.00 Nav1.1 2 5.00 sodium channel 1 5.00 Nav1.9 1 5.00

Disease Link Frequency Relevance Heat Congenital Anomalies 2 85.44 Targeted Disruption 6 75.00 Ventricular Tachycardia 22 57.76 Arrhythmogenic Right Ventricular Dysplasia 13 5.00 Heart Arrhythmia 9 5.00 Syndrome 4 5.00 Body Weight 3 5.00 Camurati-engelmann Disease 2 5.00 Adhesions 2 5.00 Bartter Syndrome 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

These hearts also showed increased expression levels of Scn1b mRNA in both ventricles and Scn5a mRNA in the right ventricles compared to findings in WT hearts.

Positive_regulation (increased) of Scn1b in ventricles

1) Confidence 0.44 Published 2008 Journal Prog Biophys Mol Biol Section Abstract Doc Link PMC2764399 Disease Relevance 0.27 Pain Relevance 0.04

General Comments

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