INT284877

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Context Info
Confidence 0.72
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 1.41
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Scn5a) plasma membrane (Scn5a) transmembrane transport (Scn5a)
Anatomy Link Frequency
ventricles 2
Scn5a (Mus musculus)
Pain Link Frequency Relevance Heat
Action potential 70 89.92 High High
nav1.3 6 63.84 Quite High
anesthesia 3 50.08 Quite High
fibrosis 66 29.52 Quite Low
addiction 16 5.00 Very Low Very Low Very Low
imagery 15 5.00 Very Low Very Low Very Low
action potential duration 10 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
Eae 6 5.00 Very Low Very Low Very Low
Nav1.1 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Body Weight 6 95.40 Very High Very High Very High
Arrhythmogenic Right Ventricular Dysplasia 26 93.84 High High
Targeted Disruption 24 88.88 High High
Congenital Anomalies 7 79.64 Quite High
Syndrome 8 77.88 Quite High
Sudden Death 6 70.08 Quite High
Arrhythmias 2 Under Development 81 69.08 Quite High
Ventricular Tachycardia 44 68.40 Quite High
Heart Rate Under Development 15 68.24 Quite High
Syncope 6 66.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Scn5a transcript levels were similar in both groups of Scn5a+/?
Transcription (levels) of Scn5a
1) Confidence 0.72 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824822 Disease Relevance 0.17 Pain Relevance 0.06
Scn5a transcript levels were similar in both groups of Scn5a+/?
Transcription (levels) of Scn5a
2) Confidence 0.69 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824822 Disease Relevance 0.17 Pain Relevance 0.06
mice with both mild and severe phenotype, showing that the phenotype heterogeneity was not due to differential transcription of the WT Scn5a allele.
Transcription (transcription) of Scn5a
3) Confidence 0.53 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824822 Disease Relevance 0.45 Pain Relevance 0.11
Scn1b and Scn5a mRNA was expressed at higher levels in the left than in the right ventricles of both Scn3b?
Transcription (expressed) of Scn5a in ventricles
4) Confidence 0.51 Published 2008 Journal Prog Biophys Mol Biol Section Abstract Doc Link PMC2764399 Disease Relevance 0.29 Pain Relevance 0.07
Secondly, ventricles of such mice showed altered expression levels of Scn3b, Scn1b and Scn5a mRNA.
Transcription (levels) of Scn5a in ventricles
5) Confidence 0.51 Published 2008 Journal Prog Biophys Mol Biol Section Body Doc Link PMC2764399 Disease Relevance 0.33 Pain Relevance 0

General Comments

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