INT284891

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Context Info
Confidence 0.03
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.32
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (FSHR) protein modification process (PLOD1) endoplasmic reticulum (PLOD1)
plasma membrane (FSHR) signal transducer activity (FSHR)
Anatomy Link Frequency
granulosa cell 2
ovaries 2
FSHR (Homo sapiens)
PLOD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 5 76.12 Quite High
agonist 4 69.04 Quite High
Dismenorea 1 32.64 Quite Low
endometriosis 5 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Polycystic Ovary Syndrome 52 89.80 High High
Syndrome 6 70.92 Quite High
Obesity 11 64.20 Quite High
Hyperinsulinism 4 62.16 Quite High
Acanthosis 1 60.80 Quite High
Endometriosis (extended) 28 60.24 Quite High
Alopecia 7 59.56 Quite High
Acne 1 58.48 Quite High
Hirsutism 26 58.24 Quite High
Hyperandrogenism 7 55.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This classic model has since been revised to take account of the induction of granulosa cell LH receptor expression by FSH during advanced stages of antral follicular development [15,103-105].
FSH Positive_regulation (induction) of Gene_expression (expression) of LH in granulosa cell
1) Confidence 0.03 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2764709 Disease Relevance 0.06 Pain Relevance 0.11
Increased Luteinizing Hormone (LH) levels, compared to the FSH, result in increased androgen production in the ovaries.
FSH Positive_regulation (result) of Gene_expression (levels) of LH in ovaries
2) Confidence 0.01 Published 2010 Journal International Journal of Trichology Section Body Doc Link PMC3002408 Disease Relevance 1.26 Pain Relevance 0

General Comments

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