INT284967

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Context Info
Confidence 0.07
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.45
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

HIST2H3C (Homo sapiens)
Pain Link Frequency Relevance Heat
Bioavailability 18 5.00 Very Low Very Low Very Low
Potency 12 5.00 Very Low Very Low Very Low
adenocard 3 5.00 Very Low Very Low Very Low
anticonvulsant 3 5.00 Very Low Very Low Very Low
headache 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myeloid Leukemia 138 90.56 High High
Myelodysplastic Syndromes 174 90.24 High High
Recurrence 9 65.20 Quite High
Disease 33 64.76 Quite High
Fever 15 61.48 Quite High
Chronic Myeloid Leukemia 15 37.36 Quite Low
Encephalopathy 6 28.80 Quite Low
Death 12 20.96 Low Low
Apoptosis 39 16.40 Low Low
Cancer 141 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Surprisingly, azacitidine alone was sufficient to increase the overall acetylation level of histones H3 and H4, which was further increased upon phenylbutyrate treatment [156].
Positive_regulation (increased) of H3
1) Confidence 0.07 Published 2008 Journal Current Medicinal Chemistry Section Body Doc Link PMC2764862 Disease Relevance 0.50 Pain Relevance 0
Surprisingly, azacitidine alone was sufficient to increase the overall acetylation level of histones H3 and H4, which was further increased upon phenylbutyrate treatment [156].
Positive_regulation (increase) of H3
2) Confidence 0.07 Published 2008 Journal Current Medicinal Chemistry Section Body Doc Link PMC2764862 Disease Relevance 0.52 Pain Relevance 0
Transient DNA hypomethylation and global histone H3 and H4 acetylation were induced, and were associated with p15 reactivation.
Positive_regulation (induced) of H3
3) Confidence 0.05 Published 2008 Journal Current Medicinal Chemistry Section Body Doc Link PMC2764862 Disease Relevance 0.42 Pain Relevance 0

General Comments

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