INT284977

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Context Info
Confidence 0.17
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.86
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (DNMT1) DNA binding (DNMT1) transcription factor binding (DNMT1)
DNMT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Bioavailability 12 5.00 Very Low Very Low Very Low
Potency 8 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
anticonvulsant 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
Myofascial pain syndrome 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apnoea 20 92.00 High High
Malocclusion 11 80.92 Quite High
Triploidy 1 78.64 Quite High
Cancer 94 70.32 Quite High
Genomic Instability 2 58.72 Quite High
Myelodysplastic Syndromes 116 50.00 Quite Low
Myeloid Leukemia 92 40.88 Quite Low
Disease 22 27.64 Quite Low
Vomiting 40 5.00 Very Low Very Low Very Low
Leukemia 36 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
After integration into DNA of replicating cells, the 5-azacytosine ring covalently bind the mantainance methyltransferase DNMT1 that is then polyubiquitinated and targeted for degradation in the proteosome [58].
DNMT1 Binding (bind) of
1) Confidence 0.17 Published 2008 Journal Current Medicinal Chemistry Section Body Doc Link PMC2764862 Disease Relevance 0.24 Pain Relevance 0
DNMT-1 is a maintenance methylase that recognizes and methylates hemi-methylated CpG dinucleotides during DNA replication allowing the propagation and conservation of DNA methylation patterns through the future generations [12].
DNMT Binding (recognizes) of
2) Confidence 0.17 Published 2008 Journal Current Medicinal Chemistry Section Body Doc Link PMC2764862 Disease Relevance 0.13 Pain Relevance 0
Associations between the Cervical Vertebral Column and Craniofacial Morphology


Aim.

Aim Binding (Associations) of
3) Confidence 0.17 Published 2010 Journal International Journal of Dentistry Section Title Doc Link PMC2901616 Disease Relevance 0.49 Pain Relevance 0

General Comments

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