INT285076

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Context Info
Confidence 0.05
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.80
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (ITK) signal transduction (ITK) extracellular space (CCL16)
extracellular region (CCL16) cytoplasm (ITK) cell-cell signaling (CCL16)
CCL16 (Homo sapiens)
ITK (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 6 97.20 Very High Very High Very High
COX-2 inhibitor 22 81.12 Quite High
diclofenac 4 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
methotrexate 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Endophthalmitis 4 91.20 High High
Retina Disease 6 89.80 High High
Macular Edema 4 89.00 High High
Ocular Hypertension 2 87.68 High High
Cataract 62 85.68 High High
Capsule Opacification 114 84.64 Quite High
Syndrome 2 81.56 Quite High
Contracture 2 81.20 Quite High
Cancer 12 80.08 Quite High
Apoptosis 32 67.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have discovered cataractous LEC that have undergone EMT express COX-2 mRNA and protein, but normal LEC do not.
LEC Positive_regulation (undergone) of Gene_expression (express) of EMT
1) Confidence 0.05 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2765474 Disease Relevance 1.12 Pain Relevance 0.05
Preliminary data obtained in our laboratory indicate that LEC undergoing EMT, have increased expression of estrogen and higher levels of aromatase activity compared to normal LEC [67].
LEC Positive_regulation (increased) of Gene_expression (undergoing) of EMT
2) Confidence 0.04 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2765474 Disease Relevance 0.68 Pain Relevance 0.09

General Comments

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