INT285151

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Context Info
Confidence 0.02
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.24
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (NGFR) endosome (NGFR) nucleoplasm (NGFR)
cytoplasm (NGFR) signal transducer activity (NGFR) cytosol (NGFR)
Anatomy Link Frequency
hinge 2
NGFR (Homo sapiens)
Pain Link Frequency Relevance Heat
Nerve growth factor 1 99.78 Very High Very High Very High
Pain 3 5.00 Very Low Very Low Very Low
Antiemetics 1 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acquired Immune Deficiency Syndrome Or Hiv Infection 147 95.44 Very High Very High Very High
Hepatitis 1 77.52 Quite High
Infection 21 5.00 Very Low Very Low Very Low
Lymphatic System Cancer 4 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Subacute Sclerosing Panencephalitis 2 5.00 Very Low Very Low Very Low
Leukemia 2 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Congenital Anomalies 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For this C46 transgene, the signal peptide of the low-affinity nerve growth factor receptor (LNGFR) directs translocation into the endoplasmic reticulum, and the human immunoglobulin G2 (IgG2) hinge fused to the human CD34 membrane-spanning domain serves as a scaffold to anchor the peptide to the cell surface [23].
Regulation (directs) of Localization (translocation) of LNGFR in hinge associated with nerve growth factor
1) Confidence 0.02 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2765621 Disease Relevance 0.24 Pain Relevance 0.05

General Comments

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