INT285168

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Context Info
Confidence 0.11
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

MALAT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
hCN2 8 96.80 Very High Very High Very High
HCN1 46 94.16 High High
addiction 1 5.00 Very Low Very Low Very Low
local anesthetic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Heart Rate Under Development 2 5.00 Very Low Very Low Very Low
Hypertension 1 5.00 Very Low Very Low Very Low
Hypertrophy 1 5.00 Very Low Very Low Very Low
Myocardial Infarction 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although chemical and structural differences exist for ZD7288 and other HCN channel blockers (such as ivabradine, cilobradine, and zatebradine), Ile432 of HCN2, a residue homologous to Val379 in the MFV377–379 triplet of HCN1, has also been shown to be involved in cilobradine binding [12].
Gene_expression (exist) of HCN associated with hcn1 and hcn2
1) Confidence 0.11 Published 2009 Journal Pflugers Arch Section Body Doc Link PMC2765624 Disease Relevance 0 Pain Relevance 0.12

General Comments

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