INT285408

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Context Info
Confidence 0.22
First Reported 2009
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.06
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transferase activity, transferring glycosyl groups (A4GALT) Golgi apparatus (A4GALT) plasma membrane organization (A4GALT)
A4GALT (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 6 5.00 Very Low Very Low Very Low
imagery 6 5.00 Very Low Very Low Very Low
fibrosis 4 5.00 Very Low Very Low Very Low
Neuropathic pain 4 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Peripheral nervous system 1 5.00 Very Low Very Low Very Low
Quantitative sensory testing 1 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fabry Disease 72 61.44 Quite High
Aging 1 34.76 Quite Low
Disease 15 5.00 Very Low Very Low Very Low
Coronary Heart Disease 8 5.00 Very Low Very Low Very Low
Renal Disease 6 5.00 Very Low Very Low Very Low
Chronic Renal Failure 6 5.00 Very Low Very Low Very Low
Fibrosis 5 5.00 Very Low Very Low Very Low
Pain 5 5.00 Very Low Very Low Very Low
Neuropathic Pain 4 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The authors concluded that high dose treatment may be more effective in reducing Gb3-levels, however, following treatment failure seven patients in this cohort received increased dosages of Agalsidase during the study, and five of them developed worsening of ischemic lesions in the CNS.
Spec (may) Regulation (effective) of Gene_expression (reducing) of Gb3
1) Confidence 0.22 Published 2009 Journal Orphanet J Rare Dis Section Body Doc Link PMC2768700 Disease Relevance 0.06 Pain Relevance 0

General Comments

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