INT285409

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Context Info
Confidence 0.27
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.21
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (ELF3) nucleolus (ELF3) nucleus (ELF3)
extracellular matrix organization (ELF3) embryo development (ELF3) cytoplasm (ELF3)
ELF3 (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 4 45.92 Quite Low
Pain 11 23.92 Low Low
imagery 10 21.36 Low Low
Neuropathic pain 4 5.00 Very Low Very Low Very Low
Central nervous system 3 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Peripheral nervous system 1 5.00 Very Low Very Low Very Low
Quantitative sensory testing 1 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 24 99.64 Very High Very High Very High
Renal Disease 6 96.80 Very High Very High Very High
Hepatomegaly 1 91.60 High High
Splenomegaly 1 90.80 High High
Fabry Disease 72 85.52 High High
Proteinuria 1 80.48 Quite High
Chronic Renal Failure 6 76.16 Quite High
Gauchers Disease 30 71.60 Quite High
Albuminuria 2 59.04 Quite High
Lysosome Storage Disease 2 58.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Overall, 21 (34%) patients were splenectomized: 5 before diagnosis, 16 between diagnosis and ERT onset; none were splenectomized after starting ERT.
Positive_regulation (splenectomized) of Positive_regulation (starting) of ERT
1) Confidence 0.27 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2945057 Disease Relevance 0.25 Pain Relevance 0
These changes were observed in an early stage of the disease, and the authors speculated on its value as an indicator for ERT efficacy.
Positive_regulation (speculated) of Positive_regulation (indicator) of ERT associated with disease
2) Confidence 0.23 Published 2009 Journal Orphanet J Rare Dis Section Body Doc Link PMC2768700 Disease Relevance 0.95 Pain Relevance 0

General Comments

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