INT285435

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Context Info
Confidence 0.62
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.90
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TLR4) plasma membrane (TLR4) intracellular (TLR4)
cytoplasm (TLR4)
Anatomy Link Frequency
extracellular matrix 1
TLR4 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 68 76.76 Quite High
Inflammatory response 26 29.68 Quite Low
cytokine 56 5.00 Very Low Very Low Very Low
agonist 54 5.00 Very Low Very Low Very Low
fibrosis 18 5.00 Very Low Very Low Very Low
chemokine 11 5.00 Very Low Very Low Very Low
tolerance 9 5.00 Very Low Very Low Very Low
Bile 5 5.00 Very Low Very Low Very Low
metalloproteinase 5 5.00 Very Low Very Low Very Low
alcohol 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 2 94.44 High High
Injury 31 93.28 High High
Cancer 3 82.76 Quite High
Vesicular Stomatitis 1 81.56 Quite High
Respiratory Syncytial Virus 1 80.68 Quite High
Communicable Diseases 2 78.12 Quite High
INFLAMMATION 93 76.76 Quite High
Infection 12 59.40 Quite High
Cryptosporidiosis 1 59.00 Quite High
Cirrhosis 61 28.96 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In vivo, damage signals and intact extracellular matrix (ECM) degradation activate TLR4 [52].
Protein_catabolism (degradation) of TLR4 in extracellular matrix
1) Confidence 0.62 Published 2010 Journal Fibrogenesis Tissue Repair Section Body Doc Link PMC2984459 Disease Relevance 0.90 Pain Relevance 0.14
Conjunctival and limbal cell samples with positive expression of TLR4 and 9 proteins were used.
Protein_catabolism (proteins) of TLR4
2) Confidence 0.59 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2768757 Disease Relevance 0 Pain Relevance 0

General Comments

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