INT285441

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Context Info
Confidence 0.38
First Reported 2007
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.15
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TLR4) plasma membrane (TLR4) intracellular (TLR4)
cytoplasm (TLR4)
Anatomy Link Frequency
corneal epithelial cells 2
TLR4 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 33 90.64 High High
Inflammatory response 12 88.76 High High
Inflammation 8 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
lidocaine 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 20 88.36 High High
Hypersensitivity 3 48.88 Quite Low
Mycobacterial Infection 27 5.00 Very Low Very Low Very Low
Cadaver 4 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Respiratory Disease 3 5.00 Very Low Very Low Very Low
Pseudomonas Infection 2 5.00 Very Low Very Low Very Low
Herpes Simplex Virus 2 5.00 Very Low Very Low Very Low
Infection 2 5.00 Very Low Very Low Very Low
Bacterial Respiratory Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Quantitative real-time PCR (qRT-PCR, TaqMan) was performed to determine the relative TLR2, TLR4 and TLR9 mRNA expression levels using the comparative threshold cycle (??
Spec (determine) Regulation (using) of Spec (determine) Localization (relative) of TLR4
1) Confidence 0.38 Published 2010 Journal Respir Res Section Body Doc Link PMC2817655 Disease Relevance 0 Pain Relevance 0
However, a later report from Ueta et al. [17] showed that LPS incubation had no effect on TLR4 surface distribution or IL-6 and IL-8 secretion in either primary cultured or immortalized human corneal epithelial cells.
Neg (no) Regulation (effect) of Localization (distribution) of TLR4 in corneal epithelial cells
2) Confidence 0.21 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2768757 Disease Relevance 0.15 Pain Relevance 0.12

General Comments

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