INT285456

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Context Info
Confidence 0.13
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 0.08
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PNP) small molecule metabolic process (PNP) cytoskeleton (PNP)
intracellular (PNP) cytoplasm (PNP)
Anatomy Link Frequency
ARPE-19 1
PNP (Homo sapiens)
Pain Link Frequency Relevance Heat
adenocard 5 45.92 Quite Low
anesthesia 5 31.20 Quite Low
Disease Link Frequency Relevance Heat
Cytomegalovirus Infection 5 79.40 Quite High
Disorders Of Creatine Metabolism 10 48.56 Quite Low
Age-related Macular Degeneration 25 5.00 Very Low Very Low Very Low
Stress 10 5.00 Very Low Very Low Very Low
Diabetic Retinopathy 5 5.00 Very Low Very Low Very Low
Uveitis 5 5.00 Very Low Very Low Very Low
Toxicity 5 5.00 Very Low Very Low Very Low
Cataract 5 5.00 Very Low Very Low Very Low
Eye Disease 5 5.00 Very Low Very Low Very Low
Retina Disease 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
g pSOD-encapsulated in HSA NP produced 5 fold higher SOD1 activity compared to untreated cells.
Positive_regulation (encapsulated) of NP
1) Confidence 0.13 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2768759 Disease Relevance 0 Pain Relevance 0
Safety of HSA NP as a gene delivery vector was evaluated by determining its cytotoxicity in ARPE-19 cells using MTT assay.
Positive_regulation (Safety) of NP in ARPE-19
2) Confidence 0.13 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2768759 Disease Relevance 0 Pain Relevance 0
Twenty-four hours post seeding, cells were transfected for 6 h with pSOD, pSOD-encapsulated in HSA NP or pSOD with 37.5 ?
Positive_regulation (encapsulated) of NP
3) Confidence 0.13 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2768759 Disease Relevance 0 Pain Relevance 0
Influence of pSOD encapsulation towards zeta potential was also reflected by the higher zeta potential of pSOD-loaded NP relative to blank NP.
Positive_regulation (potential) of NP
4) Confidence 0.13 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2768759 Disease Relevance 0 Pain Relevance 0
pSOD-encapsulated HSA NP was prepared using a modified desolvation-crosslinking method [28].
Positive_regulation (encapsulated) of NP
5) Confidence 0.13 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2768759 Disease Relevance 0.08 Pain Relevance 0

General Comments

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