INT285467

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Context Info
Confidence 0.05
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.33
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL1B, IL1RN) extracellular region (IL1B, IL1RN) aging (IL1B)
intracellular (IL1RN) cytoplasm (IL1RN) cell-cell signaling (IL1B)
IL1B (Homo sapiens)
IL1RN (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 4 99.96 Very High Very High Very High
rheumatoid arthritis 88 98.48 Very High Very High Very High
anakinra 4 94.16 High High
cytokine 53 93.52 High High
psoriasis 44 83.00 Quite High
Etanercept 8 68.96 Quite High
Arthritis 26 59.52 Quite High
Multiple sclerosis 48 54.84 Quite High
Inflammation 44 53.32 Quite High
methotrexate 5 46.68 Quite Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 89 98.48 Very High Very High Very High
Autoimmune Disease 33 97.52 Very High Very High Very High
Psoriasis 49 83.00 Quite High
Disease 69 82.40 Quite High
Latent Tuberculosis 1 76.16 Quite High
Recurrence 1 75.24 Quite High
Communicable Diseases 1 74.60 Quite High
Arthritis 16 59.52 Quite High
Multiple Sclerosis 57 54.84 Quite High
Inflammatory Bowel Disease 2 53.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IL-1 receptor antagonist (IL-1Ra) acts as a natural IL-1 inhibitor preventing the interaction of IL-1 with its cell surface receptors.
Negative_regulation (preventing) of IL-1 Binding (interaction) of IL-1Ra associated with antagonist
1) Confidence 0.05 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2768824 Disease Relevance 1.33 Pain Relevance 0.61

General Comments

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