INT285494

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Context Info
Confidence 0.40
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.48
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Fgf7) extracellular region (Fgf7) Golgi apparatus (Fgf7)
Anatomy Link Frequency
connective tissue 2
papilla 2
Fgf7 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 61 99.48 Very High Very High Very High
Inflammation 70 63.84 Quite High
psoriasis 45 23.92 Low Low
Inflammatory response 5 22.48 Low Low
chemokine 17 21.56 Low Low
rheumatoid arthritis 88 7.24 Low Low
Multiple sclerosis 48 5.00 Very Low Very Low Very Low
Arthritis 26 5.00 Very Low Very Low Very Low
Adalimumab 9 5.00 Very Low Very Low Very Low
fibrosis 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypersensitivity 1 98.80 Very High Very High Very High
Systemic Sclerosis 34 91.72 High High
Alopecia 3 81.72 Quite High
Diffuse Scleroderma 1 77.92 Quite High
Limited Scleroderma 1 73.68 Quite High
Adhesions 3 67.36 Quite High
Skin Abnormalities 2 64.40 Quite High
INFLAMMATION 74 63.84 Quite High
Psoriasis 56 56.08 Quite High
Autoimmune Disease 33 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It was recently reported that expression of FGF7 and FGF10 increases in the dermal papilla during the transition from early to late telogen.
Positive_regulation (increases) of Gene_expression (expression) of FGF7 in papilla
1) Confidence 0.40 Published 2010 Journal The Journal of Cell Biology Section Body Doc Link PMC2845079 Disease Relevance 0.34 Pain Relevance 0.03
Cytokine or cytokine receptor patterns showed high expression of CCR1, FGFR1, connective tissue growth factor (CTGF), FGF7, and SCYA19 in biopsies from SSC patients.
Positive_regulation (high) of Gene_expression (expression) of FGF7 in connective tissue associated with hypersensitivity and cytokine
2) Confidence 0.17 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2768824 Disease Relevance 1.14 Pain Relevance 0.10

General Comments

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