INT285504

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Context Info
Confidence 0.44
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.31
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Cdc7) cell cycle (Cdc7) cell division (Cdc7)
kinase activity (Cdc7) cytoplasm (Cdc7)
Cdc7 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 54 88.48 High High
rheumatoid arthritis 88 5.00 Very Low Very Low Very Low
Multiple sclerosis 48 5.00 Very Low Very Low Very Low
Inflammation 45 5.00 Very Low Very Low Very Low
psoriasis 44 5.00 Very Low Very Low Very Low
Arthritis 26 5.00 Very Low Very Low Very Low
chemokine 17 5.00 Very Low Very Low Very Low
Adalimumab 9 5.00 Very Low Very Low Very Low
fibrosis 8 5.00 Very Low Very Low Very Low
Etanercept 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 10 99.32 Very High Very High Very High
Necrosis 5 99.08 Very High Very High Very High
Skin Diseases 2 93.56 High High
Systemic Sclerosis 34 76.80 Quite High
Glaucoma 31 76.28 Quite High
Myopia 19 75.32 Quite High
Disease 75 74.72 Quite High
Limited Scleroderma 1 74.60 Quite High
Eye Disease 2 73.64 Quite High
Diffuse Scleroderma 1 72.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
19) within 117 kb of the CDC7 gene and rs1900004 on chromosome 10q21.3-q22.1 (p?
Gene_expression (gene) of CDC7
1) Confidence 0.44 Published 2010 Journal PLoS Genetics Section Abstract Doc Link PMC2883590 Disease Relevance 0.30 Pain Relevance 0
These highly expressed genes included cell cycle genes CENPE, CDC7 and CDT1, FGF5, tumor necrosis factor receptor superfamily member 12A (TNFRSF12A) and TRAF interacting protein (TRIP).
Gene_expression (expressed) of CDC7 associated with necrosis and cancer
2) Confidence 0.17 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2768824 Disease Relevance 1.01 Pain Relevance 0.10

General Comments

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