INT285510

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Context Info
Confidence 0.14
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 6.13
Pain Relevance 1.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Hand1) nucleoplasm (Hand1) enzyme binding (Hand1)
DNA binding (Hand1) cytoplasm (Hand1) nucleolus (Hand1)
Anatomy Link Frequency
B cells 6
macrophages 1
NK cells 1
mast cells 1
neutrophils 1
Hand1 (Mus musculus)
Pain Link Frequency Relevance Heat
beta blocker 1 95.88 Very High Very High Very High
psoriasis 312 92.16 High High
cytokine 277 87.64 High High
rheumatoid arthritis 440 81.24 Quite High
Arthritis 139 68.88 Quite High
depression 1 50.52 Quite High
Inflammation 225 43.80 Quite Low
anakinra 20 19.12 Low Low
Etanercept 50 11.36 Low Low
Multiple sclerosis 240 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 55 98.84 Very High Very High Very High
Obesity 3 98.80 Very High Very High Very High
Psoriasis 348 97.76 Very High Very High Very High
Nicotine Addiction 4 97.60 Very High Very High Very High
Infection 6 93.68 High High
Injury 1 93.00 High High
Inflammatory Bowel Disease 10 87.76 High High
Systemic Lupus Erythematosus 325 85.44 High High
Autoimmune Disease 168 85.08 High High
Rheumatoid Arthritis 445 81.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, it is critically involved in Th1 and Th17 polarization and it induces effector functions in mast cells, neutrophils, NK cells, B cells, macrophages and DCs.
Regulation (involved) of in mast cells Localization (polarization) of Th1 in B cells
1) Confidence 0.14 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2768824 Disease Relevance 0.97 Pain Relevance 0.25
Pathogenetic models: relevance of Th1 and Th17 responses
Regulation (responses) of Localization (relevance) of Th1
2) Confidence 0.13 Published 2010 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2880344 Disease Relevance 1.26 Pain Relevance 0.37
Moreover, it is critically involved in Th1 and Th17 polarization and it induces effector functions in mast cells, neutrophils, NK cells, B cells, macrophages and DCs.
Regulation (involved) of in neutrophils Localization (polarization) of Th1 in B cells
3) Confidence 0.05 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2768824 Disease Relevance 0.97 Pain Relevance 0.25
Moreover, it is critically involved in Th1 and Th17 polarization and it induces effector functions in mast cells, neutrophils, NK cells, B cells, macrophages and DCs.
Regulation (involved) of in NK cells Localization (polarization) of Th1 in B cells
4) Confidence 0.05 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2768824 Disease Relevance 0.97 Pain Relevance 0.25
Moreover, it is critically involved in Th1 and Th17 polarization and it induces effector functions in mast cells, neutrophils, NK cells, B cells, macrophages and DCs.
Regulation (involved) of Localization (polarization) of Th1 in B cells
5) Confidence 0.05 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2768824 Disease Relevance 0.97 Pain Relevance 0.25
Moreover, it is critically involved in Th1 and Th17 polarization and it induces effector functions in mast cells, neutrophils, NK cells, B cells, macrophages and DCs.
Regulation (involved) of in macrophages Localization (polarization) of Th1 in B cells
6) Confidence 0.05 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2768824 Disease Relevance 0.97 Pain Relevance 0.25

General Comments

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