INT285570

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Context Info
Confidence 0.11
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.76
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (IL8) extracellular space (IL8) extracellular region (IL8)
nucleus (Cdkn1c) intracellular (IL8) cell cycle (Cdkn1c)
IL8 (Homo sapiens)
Cdkn1c (Mus musculus)
Pain Link Frequency Relevance Heat
psoriasis 44 83.08 Quite High
Inflammation 44 76.16 Quite High
cytokine 53 62.80 Quite High
chemokine 17 58.68 Quite High
rheumatoid arthritis 88 43.28 Quite Low
Multiple sclerosis 48 5.00 Very Low Very Low Very Low
Arthritis 26 5.00 Very Low Very Low Very Low
Adalimumab 9 5.00 Very Low Very Low Very Low
Etanercept 8 5.00 Very Low Very Low Very Low
fibrosis 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 69 98.28 Very High Very High Very High
Psoriasis 49 84.00 Quite High
INFLAMMATION 45 76.16 Quite High
Autoimmune Disease 33 50.00 Quite Low
Rheumatoid Arthritis 89 43.28 Quite Low
Systemic Lupus Erythematosus 65 5.00 Very Low Very Low Very Low
Multiple Sclerosis 57 5.00 Very Low Very Low Very Low
Systemic Sclerosis 34 5.00 Very Low Very Low Very Low
Arthritis 16 5.00 Very Low Very Low Very Low
Apoptosis 11 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Statistical analysis using support vector machines showed that a combination of both IL-8 and CDKN1C was able to differentiate between the two disease stages with high prediction accuracy, which argues for a functional link between both molecules.
IL-8 Binding (combination) of CDKN1C associated with disease
1) Confidence 0.11 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2768824 Disease Relevance 0.76 Pain Relevance 0.34

General Comments

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