INT285664

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Context Info
Confidence 0.05
First Reported 2009
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.66
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Itk) kinase activity (Itk) cytoplasm (Itk)
Itk (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 29 85.72 High High
COX-2 inhibitor 2 60.00 Quite High
cINOD 8 41.28 Quite Low
Pain 2 32.12 Quite Low
agonist 22 5.00 Very Low Very Low Very Low
imagery 15 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
abdominal pain 2 5.00 Very Low Very Low Very Low
Crohn's disease 2 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 260 99.80 Very High Very High Very High
Metastasis 55 99.52 Very High Very High Very High
Carcinoma 22 98.68 Very High Very High Very High
Malignant Neoplastic Disease 4 91.72 High High
INFLAMMATION 31 85.72 High High
Adhesions 4 74.12 Quite High
Pancreatic Cancer 2 69.92 Quite High
Colon Cancer 30 58.84 Quite High
Lung Cancer 30 50.00 Quite Low
Gastrointestinal Neoplasms 16 42.40 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
EMT could be a reversible, dynamic process and may be regulated by the tumour microenvironment, carcinoma cells that have undergone EMT during invasion seem to regain their epithelial characteristics at the metastatic sites [24].
Spec (may) Regulation (regulated) of EMT associated with cancer and carcinoma
1) Confidence 0.05 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2912267 Disease Relevance 0.36 Pain Relevance 0
EMT is regulated by multiple signaling pathways [104].
Regulation (regulated) of EMT
2) Confidence 0.04 Published 2009 Journal PPAR Research Section Body Doc Link PMC2770108 Disease Relevance 0.80 Pain Relevance 0.07
The surprising function of Sox10 in the regulation of EMT/MET in G-2 CCS as well as the transcriptional targets of Sox10 remains to be elucidated.
Regulation (regulation) of EMT
3) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2920333 Disease Relevance 0.06 Pain Relevance 0
regulates EMT and cancer metastasis are not yet well defined.

7.

Regulation (regulates) of EMT associated with cancer and metastasis
4) Confidence 0.02 Published 2009 Journal PPAR Research Section Body Doc Link PMC2770108 Disease Relevance 0.45 Pain Relevance 0

General Comments

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