INT285701

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Context Info
Confidence 0.33
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.57
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (Tpmt)
Tpmt (Rattus norvegicus)
Pain Link Frequency Relevance Heat
pruritus 3 78.16 Quite High
Inflammation 9 5.00 Very Low Very Low Very Low
methotrexate 7 5.00 Very Low Very Low Very Low
corticosteroid 4 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
headache 3 5.00 Very Low Very Low Very Low
psoriasis 2 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Onset of action 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatotoxicity 1 95.68 Very High Very High Very High
Congenital Anomalies 1 89.24 High High
Pruritus 6 78.16 Quite High
Eczema 54 73.32 Quite High
Disease 23 53.52 Quite High
Bullous Skin Disease 1 39.48 Quite Low
Dermatomyositis 1 38.68 Quite Low
Systemic Lupus Erythematosus 1 37.44 Quite Low
Organ Transplantation 3 31.60 Quite Low
Graft Vs Host Disease 1 30.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Myelotoxicity has been shown to be related to activity of thiopurine methyltransferase (TPMT), an enzyme necessary for the metabolism of azathioprine.
Positive_regulation (necessary) of TPMT
1) Confidence 0.33 Published 2008 Journal Patient preference and adherence Section Body Doc Link PMC2770385 Disease Relevance 0.57 Pain Relevance 0.04

General Comments

This test has worked.

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