INT285726

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Context Info
Confidence 0.22
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.61
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (ALB, INS) extracellular space (ALB, INS) extracellular region (ALB, INS)
transport (ALB) carbohydrate metabolic process (INS) enzyme binding (ALB)
ALB (Homo sapiens)
INS (Homo sapiens)
Pain Link Frequency Relevance Heat
Potency 9 62.08 Quite High
Pain 3 5.00 Very Low Very Low Very Low
diabetic neuropathy 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 93 98.50 Very High Very High Very High
Hypoglycemia 63 5.00 Very Low Very Low Very Low
Obesity 42 5.00 Very Low Very Low Very Low
Weight Gain 42 5.00 Very Low Very Low Very Low
Disease 9 5.00 Very Low Very Low Very Low
Body Weight 6 5.00 Very Low Very Low Very Low
Hyperglycemia 6 5.00 Very Low Very Low Very Low
Insulin Resistance 3 5.00 Very Low Very Low Very Low
Diabetic Neuropathy 3 5.00 Very Low Very Low Very Low
Overweight 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This suggests the lower within-subject variability observed with insulin detemir may be an inherent property of its ability to bind to albumin.
albumin Binding (bind) of insulin
1) Confidence 0.22 Published 2008 Journal Patient preference and adherence Section Body Doc Link PMC2770411 Disease Relevance 0.16 Pain Relevance 0.03
Klein et al (2007) reported similar findings in patients with type 2 diabetes as within-subject variability was found to be significantly lower for the albumin-bound insulin analogs insulin detemir and an experimental acylated analog, NN344, than insulin glargine (Klein et al 2007).
albumin Binding (bound) of insulin associated with diabetes mellitus
2) Confidence 0.17 Published 2008 Journal Patient preference and adherence Section Body Doc Link PMC2770411 Disease Relevance 0.23 Pain Relevance 0
Klein et al (2007) reported similar findings in patients with type 2 diabetes as within-subject variability was found to be significantly lower for the albumin-bound insulin analogs insulin detemir and an experimental acylated analog, NN344, than insulin glargine (Klein et al 2007).
albumin Binding (bound) of insulin associated with diabetes mellitus
3) Confidence 0.17 Published 2008 Journal Patient preference and adherence Section Body Doc Link PMC2770411 Disease Relevance 0.23 Pain Relevance 0

General Comments

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