INT285758

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.79
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (RETNLB, TIMP1) cell proliferation (RETNLB) aging (TIMP1)
molecular_function (RETNLB) cellular_component (RETNLB)
Anatomy Link Frequency
tendons 2
RETNLB (Homo sapiens)
TIMP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory mediators 5 100.00 Very High Very High Very High
metalloproteinase 2 100.00 Very High Very High Very High
Inflammatory response 3 95.52 Very High Very High Very High
Inflammation 18 89.72 High High
Pain 5 79.44 Quite High
cINOD 13 5.00 Very Low Very Low Very Low
corticosteroid 11 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
Lasting pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 31 100.00 Very High Very High Very High
Tendinopathy 14 97.16 Very High Very High Very High
Tendon Injuries 14 88.32 High High
Pain 6 79.44 Quite High
Pressure And Volume Under Development 2 75.40 Quite High
Injury 8 72.40 Quite High
Spontaneous Rupture 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Overuse or repetitive stretching on tendons triggered the release of pro-inflammatory mediators, which can induce expression of metalloproteinases and leads to collagen degradation.
pro-inflammatory Positive_regulation (induce) of Gene_expression (expression) of metalloproteinases in tendons associated with inflammatory mediators and metalloproteinase
1) Confidence 0.01 Published 2009 Journal Sports Med Arthrosc Rehabil Ther Technol Section Body Doc Link PMC2770552 Disease Relevance 1.79 Pain Relevance 0.55

General Comments

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