INT285910

Context Info Confidence 0.00 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.53 Pain Relevance 0

nucleus (Pten, AKT1) plasma membrane (Pten, AKT1) enzyme binding (Pten, AKT1) cytoplasm (Pten, AKT1) cell differentiation (AKT1) nucleoplasm (AKT1)

Pten (Mus musculus) AKT1 (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammation 34 23.00 Inflammatory mediators 7 16.40 chemokine 18 5.00 cytokine 17 5.00 Central nervous system 15 5.00 Inflammatory response 3 5.00 Multiple sclerosis 2 5.00 Neuritis 1 5.00 Inflammatory stimuli 1 5.00 imagery 1 5.00

Disease Link Frequency Relevance Heat Apoptosis 56 95.04 Cancer 1 89.56 Stress 2 74.56 Lyme Disease 13 50.00 INFLAMMATION 45 23.00 Neurodegenerative Disease 10 5.00 Neuroblastoma 5 5.00 Lyme Neuroborreliosis 5 5.00 Infection 5 5.00 Multiple Sclerosis 5 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Complementing the PTEN regulation of AKT1 was a decrease in transcript for CDK2 combined with transcript increases for the CDK inhibitors p21 and GSK3?.

PTEN Regulation (regulation) of AKT1

1) Confidence 0.00 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2771360 Disease Relevance 0.53 Pain Relevance 0

General Comments

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