INT285936

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.10
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.34
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (POU5F1) DNA binding (POU5F1) cytoplasm (POU5F1)
cell-cell signaling (IL17A) cytosol (POU5F1) extracellular space (IL17A)
IL17A (Homo sapiens)
POU5F1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 102 79.20 Quite High
cytokine 54 5.00 Very Low Very Low Very Low
chemokine 8 5.00 Very Low Very Low Very Low
fibrosis 6 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
Multiple sclerosis 4 5.00 Very Low Very Low Very Low
rheumatoid arthritis 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Inflammatory stimuli 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 4 91.36 High High
Keloid Scars 206 90.84 High High
INFLAMMATION 108 79.20 Quite High
Cancer 56 50.00 Quite Low
Benign Tumor 34 5.00 Very Low Very Low Very Low
Disease 32 5.00 Very Low Very Low Very Low
Cicatrix 14 5.00 Very Low Very Low Very Low
Injury 12 5.00 Very Low Very Low Very Low
Fibrosis 6 5.00 Very Low Very Low Very Low
Aging 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Similar to IL-6, IL-17 enhanced hTERT and Oct-4 expression in both SKPs and KPCs (Figure 5B).
IL-17 Positive_regulation (enhanced) of Gene_expression (expression) of Oct-4
1) Confidence 0.10 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2771422 Disease Relevance 0.09 Pain Relevance 0
Taken together, these results suggest that IL-17 induces hTERT and Oct-4 expression in SKPs and KPCs by orchestrating the downstream IL-6 paracrine loop.


IL-17 Positive_regulation (induces) of Gene_expression (expression) of Oct-4
2) Confidence 0.10 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2771422 Disease Relevance 0.25 Pain Relevance 0.04

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox