INT285939

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.76
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL6) aging (IL6) extracellular region (IL6)
chromosome (TEP1) RNA binding (TEP1) nucleus (TEP1)
Anatomy Link Frequency
mammary gland 1
IL6 (Homo sapiens)
TEP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 4 97.48 Very High Very High Very High
cytokine 27 96.88 Very High Very High Very High
Inflammatory response 2 95.80 Very High Very High Very High
Inflammation 51 76.16 Quite High
fibrosis 3 74.96 Quite High
Multiple sclerosis 2 74.00 Quite High
rheumatoid arthritis 2 71.68 Quite High
psoriasis 1 40.96 Quite Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Malignant Neoplastic Disease 3 100.00 Very High Very High Very High
Breast Cancer 1 100.00 Very High Very High Very High
INFLAMMATION 54 95.44 Very High Very High Very High
Cancer 28 92.20 High High
Aging 3 89.68 High High
Colitis 2 89.00 High High
Apoptosis 2 83.12 Quite High
Pulmonary Fibrosis 1 74.96 Quite High
Demyelinating Disease 2 74.00 Quite High
Inflammatory Bowel Disease 2 72.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IL-6 has also been demonstrated to trigger malignant features in Notch-3-expressing stem/progenitor cells from human ductal breast carcinoma and normal mammary gland [25] and further up-regulates telomerase activity in human malignancies [26], [27].
IL-6 Positive_regulation (regulates) of telomerase in mammary gland associated with malignant neoplastic disease and breast cancer
1) Confidence 0.01 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2771422 Disease Relevance 1.76 Pain Relevance 0.61

General Comments

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