INT285960

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Context Info
Confidence 0.47
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 10.02
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (WT1) nucleolus (WT1) RNA binding (WT1)
nucleus (WT1) intracellular (WT1) cytoplasm (WT1)
Anatomy Link Frequency
bone marrow 1
arm 1
WT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 7 25.00 Low Low
chemokine 8 5.00 Very Low Very Low Very Low
cytokine 7 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Freund adjuvant 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 371 100.00 Very High Very High Very High
Cold Sores 540 99.84 Very High Very High Very High
Infection 156 98.84 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 580 98.32 Very High Very High Very High
Ulcers 120 96.44 Very High Very High Very High
Leukemia 14 89.92 High High
Myeloid Leukemia 41 85.16 High High
Herpes Simplex Virus 20 75.00 Quite High
Injury 15 60.40 Quite High
Herpes Virus Infection 5 45.60 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Circumcision significantly reduced symptomatic GUD in HSV-2-seronegative men (PRR?
Negative_regulation (reduced) of GUD associated with cold sores and disease
1) Confidence 0.47 Published 2009 Journal PLoS Medicine Section Abstract Doc Link PMC2771764 Disease Relevance 3.17 Pain Relevance 0
It is noteworthy that the efficacy of circumcision for prevention of clinically observed GUD at time of a study visit (PRR?
Negative_regulation (prevention) of GUD associated with disease
2) Confidence 0.47 Published 2009 Journal PLoS Medicine Section Body Doc Link PMC2771764 Disease Relevance 1.08 Pain Relevance 0
The finding that circumcision reduced GUD in the men who remained HSV-2 seronegative throughout the trial to approximately the same degree that it reduced GUD in HSV-2 seropositive men (Table 2) suggests that circumcision primarily reduces the rate of nonherpetic ulceration.
Negative_regulation (reduced) of GUD associated with cold sores and disease
3) Confidence 0.34 Published 2009 Journal PLoS Medicine Section Body Doc Link PMC2771764 Disease Relevance 2.04 Pain Relevance 0
The point prevalence of clinically observed GUD reported at the time of a study visit was 0.8% in the intervention arm (53/6,554 visits) and 1.9% (121/6,544 visits) in the control arm (PRR?
Negative_regulation (prevalence) of GUD in arm associated with disease
4) Confidence 0.34 Published 2009 Journal PLoS Medicine Section Body Doc Link PMC2771764 Disease Relevance 1.05 Pain Relevance 0
The finding that circumcision reduced GUD in the men who remained HSV-2 seronegative throughout the trial to approximately the same degree that it reduced GUD in HSV-2 seropositive men (Table 2) suggests that circumcision primarily reduces the rate of nonherpetic ulceration.
Negative_regulation (reduced) of GUD associated with cold sores and disease
5) Confidence 0.34 Published 2009 Journal PLoS Medicine Section Body Doc Link PMC2771764 Disease Relevance 2.03 Pain Relevance 0
Reduction of bone marrow WT1 levels was observed for a subset of patients following vaccination.
Negative_regulation (Reduction) of WT1 in bone marrow
6) Confidence 0.34 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2896720 Disease Relevance 0.64 Pain Relevance 0

General Comments

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